• David Almeida - Professor of Human Development and Family Studies
    "A transdisciplinary study of human evolution and diversity not only helps us understand how and why we became who we are, it is necessary for determining how we function day-to-day. My research examines the effects of biological and self-reported indicators of daily stress on health. How we experience and respond to daily life challenges is intricately tied to the evolution of human diversity."
    David Almeida - Professor of Human Development and Family Studies
  • Eric Plutzer - Professor of Political Science
    "For problems ranging from infectious disease to racial tensions in American cities, understanding that evolution matters but that genes are not deterministic and differ in their effects depending on social behavior and environment is a powerful way to better understand and solve many human challenges. Interdisciplinary research holds great promise for using our knowledge of evolution effectively to improve the human condition."
    Eric Plutzer - Professor of Political Science
  • Peter Hatemi - Professor of Political Science
    "If we are to make any headway in fighting diseases, reducing inequalities and the internecine fighting that appears to emerge so endemically when resources are scarce, values differ, and political approaches conflict, we must utilize multiple approaches, methods, be transdisciplinary and take into account the nature of human diversity, at every level, from our genes to our social identifications."
    Peter Hatemi - Professor of Political Science
  • Heather Toomey Zimmerman - Associate Professor of Education
    “Bringing together multiple disciplines to understand how people learn and reason about complex topics such as human evolution is important for today’s schools, museums, and other educational settings. The Center offers multiple perspectives of how research in this area is conducted, which will enhance young people’s views of how scientific knowledge is developed and of human diversity.”
    Heather Toomey Zimmerman - Associate Professor of Education
  • Nina Jablonski – CHED Director and Evan Pugh Professor of Anthropology
    Human beings are products of rich and complex interactions between biology and culture that have developed over millions of years. Human evolutionary history informs our understanding of human behavior and culture, and vice versa. Examining only one side of this set of reciprocal interactions risks missing the plot entirely.
    Nina Jablonski – CHED Director and Evan Pugh Professor of Anthropology
  • Mark Shriver - Professor of Biological Anthropology
    "Our Center is important for two reasons: 1) There are many interesting questions yet to answer about human evolution and physical, behavioral, and genetic variation, and 2) There seems to be a continuing divide between what anthropologists know and how they think about human evolution and diversity and how the general public and academic colleagues in other fields think about these topics."
    Mark Shriver - Professor of Biological Anthropology
You are here: Home / Projects / Are Human Sexually Dimorphic Traits Affected by Variation in Y-Chromosomal Ampliconic Gene Copy Number?

Are Human Sexually Dimorphic Traits Affected by Variation in Y-Chromosomal Ampliconic Gene Copy Number?

Are Human Sexually Dimorphic Traits Affected by Variation in Y-Chromosomal Ampliconic Gene Copy Number?


Amount funded:  $20,000

 

Project Personnel: 

PI: Kateryna Makova, Department of Biology, Eberly College of Science

Co-I: Mark D. Shriver, Department of Anthropology, College of the Liberal Arts

Co-I: David A. Puts, Department of Anthropology, College of the Liberal Arts

Co-I: Michael DeGiorgio, Department of Biology, Eberly College of Science

Co-I: Paul Medvedev, Department of Computer Science and Engineering, College of Engineering, and Dept. of Biochemistry and Molecular Biology, Eberly College of Science

Co-I: Francesca Chiaromonte, Department of Statistics, Eberly College of Science

 

The goal of the project is to study the variation of ampliconic gene copy number in 100 human males representing the major Y-chromosomal haplogroups; 5 human males per each of 20 Y-haplogroup assayed will be studied. Ampliconic genes are male fertility genes present in multiple copies on the Y chromosome. They are important in reproduction, especially in fertility and spermatogenesis. An undergraduate student is performing Droplet Digital PCR (ddPCR) copy number assays of 9 ampliconic gene families found on the Y chromosome to determine their sizes in each individual.

Center for Human Evolution and Diversity

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